Protein Alignment ems and ISX

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001290437.1
• Gene: ISX / 91464
• HGNCID: 28084
• Length: 245
• Species: Homo sapiens
• Alignment Length: 140
• Identity: 41/140 - (29%)
• Similarity: 59/140 - (42%)
• Gaps: 41/140 - (29%)

  Fly   329 GPAAAAAAAAGL--PPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRI 391
            ||..|||:.:||  ||            :|..|        .||               :..:|:
Human    56 GPGEAAASGSGLEKPP------------KDQPQ--------EGR---------------KSKRRV 85

  Fly   392 RTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEG 456
            ||.|:..||.:||..|....|.....|..||..:||.|.:|::||||:|.|.::    .||.|..
Human    86 RTTFTTEQLHELEKIFHFTHYPDVHIRSQLAARINLPEARVQIWFQNQRAKWRK----QEKIGNL 146

  Fly   457 GSQRNMHNGS 466
            |:.:.:...|
Human   147 GAPQQLSEAS 156

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	23/55 (42%)
ISX	NP_001290437.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	38..86		14/64 (22%)
		Homeodomain	83..139	CDD:459649	23/55 (42%)