DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ems and Nkx6-3

DIOPT Version :9

Sequence 1:NP_731868.1 Gene:ems / 41697 FlyBaseID:FBgn0000576 Length:494 Species:Drosophila melanogaster
Sequence 2:NP_083278.1 Gene:Nkx6-3 / 74561 MGIID:1921811 Length:262 Species:Mus musculus


Alignment Length:248 Identity:66/248 - (26%)
Similarity:95/248 - (38%) Gaps:76/248 - (30%)


- Green bases have known domain annotations that are detailed below.


  Fly   274 PG-GPPMPQGQP-GLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAG--HVLGPAAAA 334
            || ||.:..|.| |:.||.:.|.   |.|.                  ::|.:|  ||.|     
Mouse    41 PGLGPQLAAGTPHGITDILSRPV---ATPN------------------SSLLSGYPHVAG----- 79

  Fly   335 AAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHR-----------FPGSF-------- 380
              ..||......:.|..|.           .|:.|..:|.|           :.||.        
Mouse    80 --FGGLSSQGVYYGPQVGS-----------FSKAGNEYPTRTRNCWADTGQDWRGSARPCSNTPD 131

  Fly   381 -LVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHK 444
             |.....|.|..|..|:..|:..||..||..:|:.|.||..||.:|.::|:||||||||||||.:
Mouse   132 PLSDTIHKKKHTRPTFTGHQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWR 196

  Fly   445 RMQQEDEK-------GGEGGSQRNMHNGSGDEDDDELIDMEMDECPSDEEHEL 490
            :....:..       ||..|.:      :..|::|:..:..:|....||:..|
Mouse   197 KKSALEPSSSTPRAPGGASGDR------AASENEDDEYNKPLDPDSDDEKIRL 243

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
emsNP_731868.1 Homeobox 392..444 CDD:278475 27/51 (53%)
Nkx6-3NP_083278.1 Homeobox 143..197 CDD:395001 27/53 (51%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 197..237 6/45 (13%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X14
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
43.810

Return to query results.
Submit another query.