Protein Alignment ems and Nkx6-1

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_113925.1
• Gene: Nkx6-1 / 65193
• RGDID: 69318
• Length: 365
• Species: Rattus norvegicus
• Alignment Length: 372
• Identity: 100/372 - (26%)
• Similarity: 136/372 - (36%)
• Gaps: 119/372 - (31%)

  Fly   184 APP-----AMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYP 243
            :||     :|.:.:.|   :.|...||....|.||..|||.:   |||          .||....
  Rat    19 SPPLAALHSMAEMKTP---LYPAAYPPLPTGPPSSSSSSSSS---SSP----------SPPLGAH 67

  Fly   244 KPAMMHPGGAGPMMMPGMPPAGLVRPFPMG------------PGGPPMPQGQP------------ 284
            .|..:.|..||.:...|.||..|....|.|            ..|..:|...|
  Rat    68 NPGGLKPPAAGGLSSLGSPPQQLSAATPHGINDILSRPSMPVASGAALPSASPSGSSSSSSSSAS 132

  Fly   285 ---------------------------GLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAAL 322
                                       |||...:|     :||..||
  Rat   133 ATSASAAAAAAAAAAAAAASSPAGLLAGLPRFSSL-----SPPPPPP------------------ 174

  Fly   323 QAGHVLGPAAAAAAAAGLPPHAAQFMPN------PGMARDSYQLYPWLLSRHGRI--FPHRFPGS 379
              |....|:|||.||.|..|.....:|.      ||:    .|..||   |..|:  .||:  ||
  Rat   175 --GLYFSPSAAAVAAVGRYPKPLAELPGRTPIFWPGV----MQSPPW---RDARLACTPHQ--GS 228

  Fly   380 FLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHK 444
            .|:....|.|..|..||..|:..||..||..:|:.|.||..||.:|.::|:||||||||||||.:
  Rat   229 ILLDKDGKRKHTRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTKWR 293

  Fly   445 RMQQED----EKGGEGGSQRNMHNGSGDEDDDELIDMEMDECPSDEE 487
            :....:    :|..:..::|.......:||||: .:..:|....||:
  Rat   294 KKHAAEMATAKKKQDSETERLKGTSENEEDDDD-YNKPLDPNSDDEK 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	28/51 (55%)
Nkx6-1	NP_113925.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..136		27/113 (24%)
		Repressor domain. /evidence=ECO:0000250	102..269		47/200 (24%)
		Homeobox	240..294	CDD:395001	28/53 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	295..365		9/46 (20%)
		Involved in DNA-binding. /evidence=ECO:0000250	307..365		8/34 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810