Protein Alignment ems and nkx6.2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001129256.1
• Gene: nkx6.2 / 565782
• ZFINID: ZDB-GENE-070626-1
• Length: 278
• Species: Danio rerio
• Alignment Length: 252
• Identity: 76/252 - (30%)
• Similarity: 98/252 - (38%)
• Gaps: 69/252 - (27%)

  Fly   263 PAGLVRPFPMGPGGPPMPQGQP-GLPDIKALP-----------PYINAPPELPPQHNPHLIAAAQ 315
            |||...| .:|.....:|.|.| |:.||...|           |.||
Zfish    43 PAGFKAP-SLGNLNSQIPLGTPHGISDILGRPITTAGQLLSGFPRIN------------------ 88

  Fly   316 FQMAAALQAGHVLGPAAAA---AAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFP 377
               ..|..||....|||.:   .....||..|..|.  |||.:.|    ||   |..|: |....
Zfish    89 ---GLATSAGMYFNPAAVSRYPKPLTELPGRAPIFW--PGMMQGS----PW---RDPRV-PCAAQ 140

  Fly   378 GSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTK 442
            .:.::....|.|..|..||..|:..||..||..:|:.|.||..||.:|.::|:||||||||||||
Zfish   141 ANMMLDKDGKKKHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTESQVKVWFQNRRTK 205

  Fly   443 ------------HKRMQQEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMDECPSDEE 487
                        .|:...|.||..|          |.|.|:|:..:..:|....||:
Zfish   206 WRKRHAAEMATAKKKHDSETEKMKE----------SSDNDEDDEYNKPLDPNSDDEK 252

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/67 (43%)
nkx6.2	NP_001129256.1	Homeodomain	150..208	CDD:459649	30/57 (53%)