Protein Alignment ems and nkx2.4a

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001104636.1
• Gene: nkx2.4a / 562300
• ZFINID: ZDB-GENE-030131-6336
• Length: 345
• Species: Danio rerio
• Alignment Length: 221
• Identity: 62/221 - (28%)
• Similarity: 86/221 - (38%)
• Gaps: 71/221 - (32%)

  Fly   306 HNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGR 370
            |.||  :.:||..:|  ..|:..|    :.|..|..|...:.|.|...|...|...|  ..|:..
Zfish    69 HMPH--SVSQFSHSA--MGGYCNG----SIANMGDLPSYQETMRNSAAATGWYGANP--DPRYST 123

  Fly   371 IFPHRFPG-------------------SFLVPPFR-KPKR-IRTAFSPSQLLKLEHAFESNQYVV 414
            |  .||.|                   :..:||.. .|:| .|..||.:|:.:||..|:..:|:.
Zfish   124 I--SRFMGPSTGMNMTGMGTLTGMADTTKSIPPLHAAPRRKRRVLFSQAQVCELERRFKQQKYLS 186

  Fly   415 GAERKALAQNLNLSETQVKVWFQNRRTKHKR---------MQQE--------------------D 450
            ..||:.||..::|:.||||:||||.|.|.||         :|||                    |
Zfish   187 APEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQLQQEGNLCQQQQSPRRVAVPVLVKD 251

  Fly   451 EKGGEGGS------QRNM---HNGSG 467
            .|..:.||      |:.|   .||.|
Zfish   252 GKPCQNGSNTPTPNQQQMQQQQNGGG 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/56 (43%)
nkx2.4a	NP_001104636.1	Homeodomain	161..217	CDD:459649	24/55 (44%)