Protein Alignment ems and NKX1-1

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001277008.1
• Gene: NKX1-1 / 54729
• HGNCID: 24975
• Length: 448
• Species: Homo sapiens
• Alignment Length: 499
• Identity: 115/499 - (23%)
• Similarity: 156/499 - (31%)
• Gaps: 202/499 - (40%)

  Fly    48 SGPQSPPPGERNVPGSPPQTPPATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQHLQAPHPHPHL 112
            |||::|    .::|..||  ||.     |||.|    ||||     |...||:
Human     4 SGPEAP----GDIPALPP--PPQ-----PGSGP----APPA-----PAAAAQE------------ 36

  Fly   113 SPAQQHVLHQHLLMQQQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSL 177
                                                   || .|.:.|..  .|....|.:|.|
Human    37 ---------------------------------------AM-DGRAELPA--FPRAGAPPLAAS- 58

  Fly   178 KRERSPAPPAMEQAENPAQRIQPPH-------TPPK------------SVSPQSSQP-SSSPTLL 222
              :..||.|....|..||..::|..       .|.|            .|:|.:..| :|:|...
Human    59 --DTVPAAPEGAGAARPAAPLRPTSFSVLDILDPNKFNSRRRRCVLLGPVAPAACAPCASAPCAP 121

  Fly   223 ISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGP------------G 275
            ..:....||:.::.:      :.|:...||.|   ..|..|.....||..|.            |
Human   122 APAASGRPPRAEELE------RRALAGAGGVG---AAGAEPPNAGDPFKAGEAETNDTNGYSSGG 177

  Fly   276 GPPMPQGQPGLPDIKALPPYINAPPELPPQHN------PHLIAAAQFQMA--------------- 319
            |...|....|              .|:|...:      |...||...:.|
Human   178 GGHSPSADSG--------------DEVPDDEDDDEDEAPETEAARGAEEARGGGGGLGARGSGCQ 228

  Fly   320 ----------AALQAGHVLGP------------AAAAAAAAGLPPHAAQFMPNPGMARDSYQLYP 362
                      |.:......||            .|||...||..|........|...|....
Human   229 GAAETDASPGATVDEAAAPGPRENSPVAQGPPGGAAAPGGAGTTPQGTATAAKPKRKRTGSD--- 290

  Fly   363 WLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNL 427
               |:.|                 ||:|.||||:..||:.||:.|::.:|:...||..||.:|:|
Human   291 ---SKSG-----------------KPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSL 335

  Fly   428 SETQVKVWFQNRRTKHKRMQQEDE----KGGEGGSQRNMHNGSG 467
            :|||||:||||||||.|:.....:    .||.||.......|:|
Human   336 TETQVKIWFQNRRTKWKKQNPGADTSAPTGGGGGPGPGAGPGTG 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	29/51 (57%)
NKX1-1	NP_001277008.1	Homeobox	300..352	CDD:278475	29/51 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010