Protein Alignment ems and en1b

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001013516.1
• Gene: en1b / 541371
• ZFINID: ZDB-GENE-980526-6
• Length: 274
• Species: Danio rerio
• Alignment Length: 355
• Identity: 71/355 - (20%)
• Similarity: 120/355 - (33%)
• Gaps: 127/355 - (35%)

  Fly   162 TRLSPETEQPQMAVSLKRERSPAPP-----AMEQA-------------------ENPAQRIQPPH 202
            :|.|.|:|...::.::     |:||     |.:||                   ::|..|.:...
Zfish     9 SRDSTESESVSLSPNI-----PSPPILPHQAAQQAHRTTNFFIDNILRPDFGCKKDPGSRDRAQT 68

  Fly   203 TPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLV 267
            :..::|:|...:||.:.:|...|..::..........|:..:.::.|..|.|............:
Zfish    69 SGRENVNPMVIRPSHNSSLCQDSNCSSDSTSSSSSSSPSSKQSSVKHFEGNGSTAARNGENTPSI 133

  Fly   268 RPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAA 332
            .......|.||..:.||                                          :|.||.
Zfish   134 MMVNANGGTPPAKESQP------------------------------------------LLWPAW 156

  Fly   333 AAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRK---------P 388
            .         :..::...|...                            |..||         .
Zfish   157 V---------YCTRYSDRPSSG----------------------------PRTRKLKKKKSEKED 184

  Fly   389 KRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKG 453
            ||.||||:..||.:|:..|::|:|:....|::|||.|||:|:|:|:||||:|.|.|:     ..|
Zfish   185 KRPRTAFTAEQLQRLKAEFQANRYITEQRRQSLAQELNLNESQIKIWFQNKRAKIKK-----ASG 244

  Fly   454 GEGG-----SQRNMHNGSGDEDDDELIDME 478
            .:.|     ..:.::|.|.....||..|.|
Zfish   245 YKNGLALQLMAQGLYNHSTTTVQDEKEDSE 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	28/55 (51%)
en1b	NP_001013516.1	Homeodomain	186..241	CDD:459649	27/54 (50%)
		Engrail_1_C_sig	242..272	CDD:431338	6/29 (21%)