Protein Alignment ems and Hoxa13

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001258284.1
• Gene: Hoxa13 / 500129
• RGDID: 1562483
• Length: 386
• Species: Rattus norvegicus
• Alignment Length: 356
• Identity: 81/356 - (22%)
• Similarity: 129/356 - (36%)
• Gaps: 95/356 - (26%)

  Fly   149 HNAAMASG--LSPLQTRLSPETEQPQMAVSLKRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQ 211
            |.||.|:|  .|......:..........:|....:|..|....|.:.|    |...||.:.:..
  Rat    60 HPAAAAAGGNFSVAAAAAAAAAAAANQCRNLMAHPAPLAPGAAAAYSSA----PGEAPPTAAAAA 120

  Fly   212 SSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGG 276
            ::..:::.....:|....             |.||    |.||........|.........||..
  Rat   121 AAAAAAAAAAAAASSSGG-------------PGPA----GPAGAEAAKQCSPCSAAAQSSSGPAA 168

  Fly   277 PPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVL---GPAAAAAA-- 336
            .|......|......:.|:.||           :.:.||...|||..|...:   ||||...:
  Rat   169 LPYGYFGSGYYPCARMGPHPNA-----------IKSCAQPASAAAAFADKYMDTAGPAAEEFSSR 222

  Fly   337 -----------AAGLPPHAAQFMP------------NPGMAR--------DSYQLYPWLLSR--H 368
                       ||| |.|..|.:|            .||.:|        :|||  ||.|..  :
  Rat   223 AKEFAFYHQGYAAG-PYHHHQPVPGYLDMPVVPGLGGPGESRHEPLGLPMESYQ--PWALPNGWN 284

  Fly   369 GRIF--------PHRFPGSFLVP----------PFRKPKRIRTAFSPSQLLKLEHAFESNQYVVG 415
            |:::        ||.:..:  :|          .:|:.::.|..::..||.:||..:.:|:::..
  Rat   285 GQMYCPKEQTQPPHLWKST--LPDVVSHPSDASSYRRGRKKRVPYTKVQLKELEREYATNKFITK 347

  Fly   416 AERKALAQNLNLSETQVKVWFQNRRTKHKRM 446
            .:|:.::...||||.||.:||||||.|.|::
  Rat   348 DKRRRISATTNLSERQVTIWFQNRRVKEKKV 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	20/55 (36%)
Hoxa13	NP_001258284.1	HoxA13_N	<151..222	CDD:463521	18/81 (22%)
		Homeodomain	321..377	CDD:459649	20/55 (36%)