Protein Alignment ems and MSX2

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 227
• Identity: 67/227 - (29%)
• Similarity: 98/227 - (43%)
• Gaps: 55/227 - (24%)

  Fly   247 MMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQG--QPGLPDIKALPPYINA--PPELPPQHN 307
            :..|...||.::.|..|         ||||   .:|  :.....:.:||..:.|  ..:.||:..
Human    10 LFSPDEEGPAVVAGPGP---------GPGG---AEGAAEERRVKVSSLPFSVEALMSDKKPPKEA 62

  Fly   308 PHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPP-----HAAQFMPNPG-----------MARD 356
            ..|                   ||.:|:|.|.|.|     |.|:...:||           .:.:
Human    63 SPL-------------------PAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSEN 108

  Fly   357 SYQLYPWLLSRHGRIFP---HRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAER 418
            |.....| :...||..|   |..|.:..:...:..::.||.|:.||||.||..|...||:..|||
Human   109 SEDGAAW-MQEPGRYSPPPRHMSPTTCTLRKHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAER 172

  Fly   419 KALAQNLNLSETQVKVWFQNRRTKHKRMQQED 450
            ...:.:|||:|||||:||||||.|.||:|:.:
Human   173 AEFSSSLNLTETQVKIWFQNRRAKAKRLQEAE 204

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	30/51 (59%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		18/91 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		5/30 (17%)
		Homeobox	145..199	CDD:365835	30/53 (57%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810