Protein Alignment ems and MSX1

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_002439.2
• Gene: MSX1 / 4487
• HGNCID: 7391
• Length: 303
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 80/303 - (26%)
• Similarity: 117/303 - (38%)
• Gaps: 85/303 - (28%)

  Fly   164 LSPETEQPQMAVSLKRERS----PAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLL-- 222
            ::|..:...:.:.:|.|.|    ||.....||.:.|...    ........:.::|..||:||
Human     1 MAPAADMTSLPLGVKVEDSAFGKPAGGGAGQAPSAAAAT----AAAMGADEEGAKPKVSPSLLPF 61

  Fly   223 ----ISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQ 283
                :.:.|..|..::....|....:.|   .|.|.|:   |:||..|
Human    62 SVEALMADHRKPGAKESALAPSEGVQAA---GGSAQPL---GVPPGSL----------------- 103

  Fly   284 PGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFM 348
             |.||..:.|        .|..|         |.:...|:                ||..|....
Human   104 -GAPDAPSSP--------RPLGH---------FSVGGLLK----------------LPEDALVKA 134

  Fly   349 PNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPP---FRKPK---RIRTAFSPSQLLKLEHAF 407
            .:|    :..:..||:.|  .|..|.  |...|.||   .||.|   :.||.|:.:|||.||..|
Human   135 ESP----EKPERTPWMQS--PRFSPP--PARRLSPPACTLRKHKTNRKPRTPFTTAQLLALERKF 191

  Fly   408 ESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQED 450
            ...||:..|||...:.:|:|:|||||:||||||.|.||:|:.:
Human   192 RQKQYLSIAERAEFSSSLSLTETQVKIWFQNRRAKAKRLQEAE 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	28/51 (55%)
MSX1	NP_002439.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	18..55		7/40 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	69..117		16/79 (20%)
		PTZ00449	<105..>248	CDD:185628	54/171 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	133..174		13/48 (27%)
		Homeobox	175..229	CDD:395001	28/53 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810