Protein Alignment ems and MEOX1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 87/343 - (25%)
• Similarity: 112/343 - (32%)
• Gaps: 123/343 - (35%)

  Fly   174 AVSLKRERSPAPPAMEQAENP------AQRIQPPHTPPKSVS----------PQSSQPSSSPTLL 222
            |.|..|...|..|......||      |..:  ||.||...|          ..::.|..|.:.|
Human     5 ASSCMRSLQPPAPVWGCLRNPHSEGNGASGL--PHYPPTPFSFHQKPDFLATATAAYPDFSASCL 67

  Fly   223 ISSPHATPPQQQ---QQQP----PPNYPKP---AMMHP--GGAGPMMMPGMPPAGLVRPFPMGPG 275
            .::||:.|.::.   :|.|    .||:..|   |...|  |.||.....|....|||..    .|
Human    68 AATPHSLPQEEHIFTEQHPAFPQSPNWHFPVSDARRRPNSGPAGGSKEMGTSSLGLVDT----TG 128

  Fly   276 GPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAA--AAAAAA 338
            ||....|                                            |||..|  ....::
Human   129 GPGDDYG--------------------------------------------VLGSTANETEKKSS 149

  Fly   339 GLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKL 403
            .....::....|.|....|                            .|.::.||||:..||.:|
Human   150 RRRKESSDNQENRGKPEGS----------------------------SKARKERTAFTKEQLREL 186

  Fly   404 EHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGD 468
            |..|..:.|:....|..:|.||:|||.||||||||||.|.||:     |||:..|.    ||...
Human   187 EAEFAHHNYLTRLRRYEIAVNLDLSERQVKVWFQNRRMKWKRV-----KGGQPISP----NGQDP 242

  Fly   469 EDDDELIDMEMDECPSDE 486
            ||.|....      ||.|
Human   243 EDGDSTAS------PSSE 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	28/55 (51%)
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		27/167 (16%)
		Homeodomain	172..228	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		13/41 (32%)