Protein Alignment ems and pitx3

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_991238.1
• Gene: pitx3 / 402974
• ZFINID: ZDB-GENE-041229-4
• Length: 293
• Species: Danio rerio
• Alignment Length: 191
• Identity: 45/191 - (23%)
• Similarity: 72/191 - (37%)
• Gaps: 56/191 - (29%)

  Fly   286 LPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPN 350
            |.|.:|..|.::......|||:|    ..:.|..:..:..|              ..|..:..|.
Zfish     6 LTDSEARSPALSLSDSGTPQHDP----GCKGQDNSDTEKSH--------------QNHTDESNPE 52

  Fly   351 PGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVG 415
            .|..:                              :|.:|.||.|:..||.:||..|:.|:|...
Zfish    53 DGSLK------------------------------KKQRRQRTHFTSQQLQELEATFQRNRYPDM 87

  Fly   416 AERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDE----KGGEGGSQRNMHNGSGDEDDD 472
            :.|:.:|...||:|.:|:|||:|||.|.::.::..:    |.|.|.    ..||.....||
Zfish    88 STREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQAELCKNGFGA----QFNGLMQPYDD 144

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
pitx3	NP_991238.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..69		18/110 (16%)
		Homeodomain	61..117	CDD:459649	24/55 (44%)
		OAR	251..268	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	255..268
		Nuclear localization signal. /evidence=ECO:0000250|UniProtKB:O35160	260..264