Protein Alignment ems and NKX1-2

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001139812.1
• Gene: NKX1-2 / 390010
• HGNCID: 31652
• Length: 310
• Species: Homo sapiens
• Alignment Length: 319
• Identity: 76/319 - (23%)
• Similarity: 101/319 - (31%)
• Gaps: 132/319 - (41%)

  Fly   185 PPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSS--PTLLISSPHATPP-------------QQQ 234
            |....:|..||.|..|..........::.:.:||  |...:.:|.|..|             :::
Human    28 PQKFTRAALPAVRPAPREARKSLAEVEAGKDASSRDPVRQLETPDAAGPGAGQASPLEGSEAEEE 92

  Fly   235 QQQPPPNYP----KPAMMHPGGAGPMMMPGMPPAGLV--RPFPMGPGGP-PMPQGQPGLPDIKAL 292
            :....|..|    :.|.:.||.|   ..|..|...|.  .|...|.||| ..|.|.||
Human    93 EDAEDPRRPRLRERAARLLPGLA---RSPDAPAGALASGEPCEDGGGGPVRSPPGSPG------- 147

  Fly   293 PPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDS 357
                                                                   .|.|...|
Human   148 -------------------------------------------------------SPRPRRRR-- 155

  Fly   358 YQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALA 422
                                   |.|...||:|.||||:..||:.||:.|.:.:|:...||..||
Human   156 -----------------------LEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLA 197

  Fly   423 QNLNLSETQVKVWFQNRRTKHKRMQ--------------QEDEKGGEGGSQRNMHNGSG 467
            .:|:|:|||||:||||||||.|:..              |....||.||      .|||
Human   198 LSLSLTETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGGGG------GGSG 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	29/51 (57%)
NKX1-2	NP_001139812.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..165		35/218 (16%)
		Homeobox	167..219	CDD:278475	29/51 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..260		10/40 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010