Protein Alignment ems and HOXD4

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_055436.2
• Gene: HOXD4 / 3233
• HGNCID: 5138
• Length: 255
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 70/257 - (27%)
• Similarity: 101/257 - (39%)
• Gaps: 54/257 - (21%)

  Fly   237 QPPPNYPKPAMMHP--GGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAP 299
            |||..||:|.....  ||:||.....:|..|..:. |.||||.....|:|           ..||
Human    47 QPPGLYPRPDFGEQPFGGSGPGPGSALPARGHGQE-PGGPGGHYAAPGEP-----------CPAP 99

  Fly   300 PELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWL 364
            |..||...|                    |..|.:.:....|| :...:..|.:      :|||:
Human   100 PAPPPAPLP--------------------GARAYSQSDPKQPP-SGTALKQPAV------VYPWM 137

  Fly   365 LSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSE 429
            ...|.......:.|.       :|||.|||::..|:|:||..|..|:|:....|..:|..|.|||
Human   138 KKVHVNSVNPNYTGG-------EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLSE 195

  Fly   430 TQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMDECPSDEEHELD 491
            .|:|:||||||.|.|:..:.....|...|..:..:.|......:.:.      |..::|..|
Human   196 RQIKIWFQNRRMKWKKDHKLPNTKGRSSSSSSSSSCSSSVAPSQHLQ------PMAKDHHTD 251

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
HOXD4	NP_055436.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..127		29/112 (26%)
		Antp-type hexapeptide	133..138		3/4 (75%)
		Homeodomain	155..211	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..255		6/46 (13%)