Protein Alignment ems and HOXD1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 83/292 - (28%)
• Similarity: 109/292 - (37%)
• Gaps: 108/292 - (36%)

  Fly   251 GGAGPMMMPGMP--------PAGLVRPFPMGPGGP------PMPQGQPGLPDIKALPPYINAPPE 301
            ||.|..::...|        |..|...||:|.|..      |:...:|. |...|.|...:.||.
Human    14 GGVGGDVLSLAPKFCRSDARPVALQPAFPLGNGDGAFVSCLPLAAARPS-PSPPAAPARPSVPPP 77

  Fly   302 LPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAA----AGLPPHAAQFMPNPGMARD---SYQ 359
            ..||:       ||..:..|.:.|  ..|||||..|    .|..| |..|....|.|.|   |:.
Human    78 AAPQY-------AQCTLEGAYEPG--AAPAAAAGGADYGFLGSGP-AYDFPGVLGRAADDGGSHV 132

  Fly   360 LY----------PWLLSRHGRI----------FP---------HRFPGSF------------LVP 383
            .|          .:|||  |::          ||         |  ||:|            .|.
Human   133 HYATSAVFSGGGSFLLS--GQVDYAAFGEPGPFPACLKASADGH--PGAFQTASPAPGTYPKSVS 193

  Fly   384 P------------FRKPKR-------------------IRTAFSPSQLLKLEHAFESNQYVVGAE 417
            |            :.|.||                   |||.||..||.:||..|..|:|:..|.
Human   194 PASGLPAAFSTFEWMKVKRNASKKGKLAEYGAASPSSAIRTNFSTKQLTELEKEFHFNKYLTRAR 258

  Fly   418 RKALAQNLNLSETQVKVWFQNRRTKHKRMQQE 449
            |..:|..|:|::||||:||||||.|.|:.::|
Human   259 RIEIANCLHLNDTQVKIWFQNRRMKQKKRERE 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	30/74 (41%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	27/52 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328