Protein Alignment ems and HOXC13

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_059106.2
• Gene: HOXC13 / 3229
• HGNCID: 5125
• Length: 330
• Species: Homo sapiens
• Alignment Length: 288
• Identity: 73/288 - (25%)
• Similarity: 108/288 - (37%)
• Gaps: 71/288 - (24%)

  Fly   181 RSPAPPAMEQ--------AENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSP----------- 226
            |.|||....|        |...|::..||..||         .|||.||....|
Human    80 RPPAPLGAPQGAVYTDIPAPEAARQCAPPPAPP---------TSSSATLGYGYPFGGSYYGCRLS 135

  Fly   227 HATPPQQQQQQPPPNYPKPAMMHPGGAGPM---MMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPD 288
            |....||          ||...|||...|.   .:||...:...:.|...|......|..||..|
Human   136 HNVNLQQ----------KPCAYHPGDKYPEPSGALPGDDLSSRAKEFAFYPSFASSYQAMPGYLD 190

  Fly   289 IKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGM 353
            :..:|. |:..||  |:|:. ||....:| ..||..|.     .:....:.....:|....:|
Human   191 VSVVPG-ISGHPE--PRHDA-LIPVEGYQ-HWALSNGW-----DSQVYCSKEQSQSAHLWKSP-- 243

  Fly   354 ARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAER 418
                              ||...|....|..:|:.::.|..::..||.:||..:.:::::...:|
Human   244 ------------------FPDVVPLQPEVSSYRRGRKKRVPYTKVQLKELEKEYAASKFITKEKR 290

  Fly   419 KALAQNLNLSETQVKVWFQNRRTKHKRM 446
            :.::...||||.||.:||||||.|.|::
Human   291 RRISATTNLSERQVTIWFQNRRVKEKKV 318

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	19/55 (35%)
HOXC13	NP_059106.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..50
		HoxA13_N	54..168	CDD:463521	28/106 (26%)
		Homeodomain	261..312	CDD:459649	16/50 (32%)