Protein Alignment ems and HOXC9

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_008828.1
• Gene: HOXC9 / 3225
• HGNCID: 5130
• Length: 260
• Species: Homo sapiens
• Alignment Length: 276
• Identity: 71/276 - (25%)
• Similarity: 101/276 - (36%)
• Gaps: 71/276 - (25%)

  Fly   194 PAQRIQPPHTPPKSVSPQSSQ-PSSS---PTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGG-- 252
            ||....|....|..:.|..|. ||.|   ...:.|:..|..|.|......|..|:|   |.|.
Human    29 PATGAHPAAARPSGLVPDCSDFPSCSFAPKPAVFSTSWAPVPSQSSVVYHPYGPQP---HLGADT 90

  Fly   253 ----------AGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYI-NAPPEL---P 303
                      :|.:..|..|..|  |.:.:.|...|..:...|..:.::.|.|: .:|.||   .
Human    91 RYMRTWLEPLSGAVSFPSFPAGG--RHYALKPDAYPGRRADCGPGEGRSYPDYMYGSPGELRDRA 153

  Fly   304 PQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRH 368
            ||..|                    .|.|.|.|.:......|...|:..:|.       |:.:|.
Human   154 PQTLP--------------------SPEADALAGSKHKEEKADLDPSNPVAN-------WIHARS 191

  Fly   369 GRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVK 433
            .|                   :.|..::..|.|:||..|..|.|:....|..:|:.|||:|.|||
Human   192 TR-------------------KKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLTERQVK 237

  Fly   434 VWFQNRRTKHKRMQQE 449
            :||||||.|.|:|.:|
Human   238 IWFQNRRMKMKKMNKE 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
HOXC9	NP_008828.1	Hox9_act	1..179	CDD:461369	39/174 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..181		17/80 (21%)
		Homeodomain	193..241	CDD:459649	19/66 (29%)