Protein Alignment ems and HOXC8

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_073149.1
• Gene: HOXC8 / 3224
• HGNCID: 5129
• Length: 242
• Species: Homo sapiens
• Alignment Length: 198
• Identity: 48/198 - (24%)
• Similarity: 73/198 - (36%)
• Gaps: 53/198 - (26%)

  Fly   327 VLGPAAAAAAAAGLPPHAAQFMPN--PGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVP------ 383
            |.||..:|........|...|..:  .|::...||..|..||.||.  ..:|.|...:|
Human    39 VYGPGGSAPGFQHASHHVQDFFHHGTSGISNSGYQQNPCSLSCHGD--ASKFYGYEALPRQSLYG 101

  Fly   384 --------------------------------------PFRKP-----KRIRTAFSPSQLLKLEH 405
                                                  |:.:|     :..|..:|..|.|:||.
Human   102 AQQEASVVQYPDCKSSANTNSSEGQGHLNQNSSPSLMFPWMRPHAPGRRSGRQTYSRYQTLELEK 166

  Fly   406 AFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGDED 470
            .|..|.|:....|..::..|.|:|.|||:||||||.|.|:...:|:..|....::....|:.:|:
Human   167 EFLFNPYLTRKRRIEVSHALGLTERQVKIWFQNRRMKWKKENNKDKLPGARDEEKVEEEGNEEEE 231

  Fly   471 DDE 473
            .:|
Human   232 KEE 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	23/55 (42%)
HOXC8	NP_073149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	114..154		2/39 (5%)
		Antp-type hexapeptide	138..143		1/4 (25%)
		Homeodomain	150..206	CDD:459649	23/55 (42%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	206..242		5/29 (17%)