Protein Alignment ems and HOXC6

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_004494.1
• Gene: HOXC6 / 3223
• HGNCID: 5128
• Length: 235
• Species: Homo sapiens
• Alignment Length: 222
• Identity: 56/222 - (25%)
• Similarity: 85/222 - (38%)
• Gaps: 42/222 - (18%)

  Fly   282 GQPGLPDI----KALPPY--------------INAPPELPPQHN--------PHLIAAAQFQMAA 320
            ||..||::    .|..|.              |.:.|...||.|        |:...:..|....
Human    17 GQDVLPNVALNSTAYDPVRHFSTYGAAVAQNRIYSTPFYSPQENVVFSSSRGPYDYGSNSFYQEK 81

  Fly   321 ALQAG---HVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLV 382
            .:.:.   :.||.....:.|........:..|....|  |.|:|||:    .|:..|...|.
Human    82 DMLSNCRQNTLGHNTQTSIAQDFSSEQGRTAPQDQKA--SIQIYPWM----QRMNSHSGVGY--- 137

  Fly   383 PPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQ 447
              ....:|.|..:|..|.|:||..|..|:|:....|..:|..|.|:|.|:|:||||||.|.|:..
Human   138 --GADRRRGRQIYSRYQTLELEKEFHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKES 200

  Fly   448 Q--EDEKGGEGGSQRNMHNGSGDEDDD 472
            .  ....||.||:..:...|..::.::
Human   201 NLTSTLSGGGGGATADSLGGKEEKREE 227

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
HOXC6	NP_004494.1	Antp-type hexapeptide	122..127		3/8 (38%)
		Homeodomain	142..198	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	200..235		5/28 (18%)