Protein Alignment ems and HOXC4

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_055435.2
• Gene: HOXC4 / 3221
• HGNCID: 5126
• Length: 264
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 68/265 - (25%)
• Similarity: 92/265 - (34%)
• Gaps: 81/265 - (30%)

  Fly   198 IQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKP----------AMMHPG- 251
            |.|...|.:..|..|..|..||.....:..:......|:..||..|:|          ::..||
Human    13 IDPKFPPCEEYSQNSYIPEHSPEYYGRTRESGFQHHHQELYPPPPPRPSYPERQYSCTSLQGPGN 77

  Fly   252 --GAGPMMMPGMPP---AGLVRPFPM-GPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHL 310
              |.||.......|   ..|..|.|: |....|.|           .||..:.|   .|.|
Human    78 SRGHGPAQAGHHHPEKSQSLCEPAPLSGASASPSP-----------APPACSQP---APDH---- 124

  Fly   311 IAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHR 375
                                          |..||...|         .:|||:...|.......
Human   125 ------------------------------PSSAASKQP---------IVYPWMKKIHVSTVNPN 150

  Fly   376 FPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRR 440
            :.|.       :|||.|||::..|:|:||..|..|:|:....|..:|.:|.|||.|:|:||||||
Human   151 YNGG-------EPKRSRTAYTRQQVLELEKEFHYNRYLTRRRRIEIAHSLCLSERQIKIWFQNRR 208

  Fly   441 TKHKR 445
            .|.|:
Human   209 MKWKK 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
HOXC4	NP_055435.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..130		30/158 (19%)
		Antp-type hexapeptide	135..140		3/4 (75%)
		Homeodomain	157..213	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..264		68/265 (26%)