Protein Alignment ems and HOXB8

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_076921.1
• Gene: HOXB8 / 3218
• HGNCID: 5119
• Length: 243
• Species: Homo sapiens
• Alignment Length: 257
• Identity: 65/257 - (25%)
• Similarity: 94/257 - (36%)
• Gaps: 62/257 - (24%)

  Fly   254 GPMMMPGMPPAGLVRPFPMGPGGPPM----PQGQPGLPDIKALPPYINAPPEL---PPQHNPHLI 311
            |..:.|.....|    |....||.|.    |...........:..:.:.|..|   |.|.||..:
Human    16 GESLRPNYYDCG----FAQDLGGRPTVVYGPSSGGSFQHPSQIQEFYHGPSSLSTAPYQQNPCAV 76

  Fly   312 AA----AQFQMAAALQAGHVLGPA---------AAAAAAAGLPPHA--AQFMPNPGMARDSYQLY 361
            |.    ..|.....||...:.|..         ...|||:||...|  ::..|:|      .||:
Human    77 ACHGDPGNFYGYDPLQRQSLFGAQDPDLVQYADCKLAAASGLGEEAEGSEQSPSP------TQLF 135

  Fly   362 PWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLN 426
            ||:.       |....|.         :|.|..:|..|.|:||..|..|.|:....|..::..|.
Human   136 PWMR-------PQAAAGR---------RRGRQTYSRYQTLELEKEFLFNPYLTRKRRIEVSHALG 184

  Fly   427 LSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMDECP--SDE 486
            |:|.|||:||||||.|.|:...:|:            ..|...:.:||...:::..|  :||
Human   185 LTERQVKIWFQNRRMKWKKENNKDK------------FPSSKCEQEELEKQKLERAPEAADE 234

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
HOXB8	NP_076921.1	Antp-type hexapeptide	134..139		3/4 (75%)
		Homeodomain	147..203	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	203..243		7/44 (16%)