Protein Alignment ems and HOXA6

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_076919.1
• Gene: HOXA6 / 3203
• HGNCID: 5107
• Length: 233
• Species: Homo sapiens
• Alignment Length: 255
• Identity: 55/255 - (21%)
• Similarity: 80/255 - (31%)
• Gaps: 90/255 - (35%)

  Fly   259 PGMPPAG----------------LVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHN 307
            ||..|:|                .:||||...|.             .:||......|....|.|
Human    11 PGSLPSGQDSFLGQLPLYQAGYDALRPFPASYGA-------------SSLPDKTYTSPCFYQQSN 62

  Fly   308 PHLI---AAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQ---------- 359
            ..|.   |:.::..:.......:.|.:.:.:.....|.....|.|......||..
Human    63 SVLACNRASYEYGASCFYSDKDLSGASPSGSGKQRGPGDYLHFSPEQQYKPDSSSGQGKALHDEG 127

  Fly   360 --------LYPWL----------LSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHA 406
                    :|||:          ...|||                   |.|..::..|.|:||..
Human   128 ADRKYTSPVYPWMQRMNSCAGAVYGSHGR-------------------RGRQTYTRYQTLELEKE 173

  Fly   407 FESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRM-----------QQEDEKGGE 455
            |..|:|:....|..:|..|.|:|.|:|:||||||.|.|:.           :..:.|.||
Human   174 FHFNRYLTRRRRIEIANALCLTERQIKIWFQNRRMKWKKENKLINSTQPSGEDSEAKAGE 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	23/55 (42%)
HOXA6	NP_076919.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	89..127		5/37 (14%)
		Antp-type hexapeptide	136..141		3/4 (75%)
		Homeodomain	156..212	CDD:459649	24/74 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..233		1/18 (6%)