Protein Alignment ems and HOXA5

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_061975.2
• Gene: HOXA5 / 3202
• HGNCID: 5106
• Length: 270
• Species: Homo sapiens
• Alignment Length: 252
• Identity: 67/252 - (26%)
• Similarity: 92/252 - (36%)
• Gaps: 72/252 - (28%)

  Fly   224 SSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPD 288
            :|..|.|.:.:..||..:...|            .|...|...|.|   .||......|:..|.:
Human    75 ASASAAPAEPRYSQPATSTHSP------------QPDPLPCSAVAP---SPGSDSHHGGKNSLSN 124

  Fly   289 IKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAG--HV-----LGPAAAAA--AAAGLPPHA 344
                                        ...|:..||  |:     :|.|:.|.  |.|.....:
Human   125 ----------------------------SSGASADAGSTHISSREGVGTASGAEEDAPASSEQAS 161

  Fly   345 AQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFES 409
            ||..|:|...... |:|||:...|   ..|...|.      .:.||.|||::..|.|:||..|..
Human   162 AQSEPSPAPPAQP-QIYPWMRKLH---ISHDNIGG------PEGKRARTAYTRYQTLELEKEFHF 216

  Fly   410 NQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEK------GGEGGSQR 460
            |:|:....|..:|..|.|||.|:|:||||||.|.|:    |.|      ...||:.|
Human   217 NRYLTRRRRIEIAHALCLSERQIKIWFQNRRMKWKK----DNKLKSMSMAAAGGAFR 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
HOXA5	NP_061975.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	75..175		27/143 (19%)
		Antp-type hexapeptide	176..181		3/4 (75%)
		Homeodomain	196..252	CDD:459649	27/55 (49%)