Protein Alignment ems and TLX1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_011538046.1
• Gene: TLX1 / 3195
• HGNCID: 5056
• Length: 342
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 72/230 - (31%)
• Similarity: 95/230 - (41%)
• Gaps: 38/230 - (16%)

  Fly   251 GGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQ 315
            ||.|.....|...||...  ..|||||..|.|..|...:..|....|....|.....|.....:.
Human    58 GGGGSAAATGAGGAGAYG--TGGPGGPGGPAGGGGACSMGPLTGSYNVNMALAGGPGPGGGGGSS 120

  Fly   316 FQMAAALQAGHVLGPA----AAAAA-----AAGLPPHAAQFMPN----PGMARDSYQLYPWLLSR 367
            ....|...||.:..||    |.|.|     |.|||.     :|:    ||:...:...:||:.|.
Human   121 GGAGALSAAGVIRVPAHRPLAGAVAHPQPLATGLPT-----VPSVPAMPGVNNLTGLTFPWMESN 180

  Fly   368 HGRIFPHRF---------------PGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAE 417
            . |....||               |.....||  |.|:.||:|:..|:.:||..|...:|:..||
Human   181 R-RYTKDRFTVALSPFTVTRRIGHPYQNRTPP--KKKKPRTSFTRLQICELEKRFHRQKYLASAE 242

  Fly   418 RKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEK 452
            |.|||:.|.:::.|||.||||||||.:|...|:.:
Human   243 RAALAKALKMTDAQVKTWFQNRRTKWRRQTAEERE 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
TLX1	XP_011538046.1	Homeodomain	214..270	CDD:459649	27/55 (49%)