Protein Alignment ems and HMX2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_005510.1
• Gene: HMX2 / 3167
• HGNCID: 5018
• Length: 273
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 67/259 - (25%)
• Similarity: 93/259 - (35%)
• Gaps: 87/259 - (33%)

  Fly   191 AENPAQRI-QPPHTPPKSVSPQSSQPS---SSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPG 251
            :|.|.:.: .|......|||.:..:|.   .:|.......|.  |::|..:..|..|.|.:..|.
Human    31 SEAPREPVGWPARKRSLSVSSEEEEPDDGWKAPACFCPDQHG--PKEQGPKHHPPIPFPCLGTPK 93

  Fly   252 GAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQF 316
            |:|                ..||||                   :...|.|.|.|:..     :.
Human    94 GSG----------------GSGPGG-------------------LERTPFLSPSHSDF-----KE 118

  Fly   317 QMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFL 381
            :....|.||                      .|:||..|          .|.|.  ..|..|:
Human   119 EKERLLPAG----------------------SPSPGSER----------PRDGG--AERQAGA-- 147

  Fly   382 VPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKR 445
                 ..|:.||.||.||:.:||..|:..:|:..:||..||.:|.|:|||||.||||||.|.||
Human   148 -----AKKKTRTVFSRSQVYQLESTFDMKRYLSSSERACLASSLQLTETQVKTWFQNRRNKWKR 206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)
HMX2	NP_005510.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		37/203 (18%)
		Homeodomain	150..206	CDD:459649	29/55 (53%)