Protein Alignment ems and Vsx2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001284897.1
• Gene: Vsx2 / 31469
• FlyBaseID: FBgn0263512
• Length: 645
• Species: Drosophila melanogaster
• Alignment Length: 538
• Identity: 117/538 - (21%)
• Similarity: 161/538 - (29%)
• Gaps: 224/538 - (41%)

  Fly    17 MPTPKQKIGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNVPGSPPQTPPATLTLIPGSPPH 81
            ||   |:..|:|:.::|..|:.|....|...:...:....||..| :||:|..||:.....|..
  Fly     1 MP---QRSPFAIQELLGLAVAAATEAPTDLTTTAGATVAKERQTP-TPPKTTNATMATAATSAA- 60

  Fly    82 HLMAPPAHGL---------PYPHPHAQQQHLQAPHPHPHLSPAQQHVLHQHLLMQQQHPGTPKSH 137
             ..|.|.:..         |...|..|||.             |||  ||           |..|
  Fly    61 -TAATPTNAAEGNLTSVSEPQQQPQQQQQE-------------QQH--HQ-----------PHHH 98

  Fly   138 QDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSLKRERSPAPPAMEQAENPAQRIQPPH 202
            |      .|.||...||:.     :|::.......:|.:..                      ||
  Fly    99 Q------YREHHQMTMAAA-----SRMAYFNAHAAVAAAFM----------------------PH 130

  Fly   203 TPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLV 267
            ....:|....                   |.|.|..|.::|.    ||.||
  Fly   131 QLAAAVHHHH-------------------QHQHQHHPHHHPH----HPHGA-------------- 158

  Fly   268 RPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPH--LIAAAQFQMAAALQAGHVLGP 330
                  .||||.|            ||..:..|     |:||  |:.|..|....:..||
  Fly   159 ------VGGPPPP------------PPMQHHHP-----HHPHHPLLHAQGFPQLKSFAAG----- 195

  Fly   331 AAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFP----GSFLVPPFRKPKR- 390
                 |...||                           |.:.|..|.    ..|.|.|..|.|:
  Fly   196 -----AGTCLP---------------------------GSLAPKDFGMESLNGFGVGPNSKKKKK 228

  Fly   391 ----IRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQ--- 448
                .||.|:..||.|||.||:...|.....|:.|:....|.|.:::|||||||.|.::.::
  Fly   229 KRRHSRTIFTSYQLEKLEEAFKEAHYPDVYAREMLSLKTELPEDRIQVWFQNRRAKWRKTEKVWG 293

  Fly   449 --------------------------EDEKGGE-------GGSQRNMHNGSGD-----EDDDELI 475
                                      :..|..:       |..|:.||..|.:     :||..:.
  Fly   294 GSTIMAEYGLYGAMVRHSLPLPDTILKSAKDNDAVAPWLLGMEQKCMHRKSIEAQSALKDDSGVS 358

  Fly   476 DMEMDECPSDEEHELDAS 493
            |.| |...|...|..|.|
  Fly   359 DHE-DSAGSKSAHSEDLS 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/60 (40%)
Vsx2	NP_001284897.1	Homeodomain	230..287	CDD:459649	23/56 (41%)
		OAR	556..572	CDD:461067