Protein Alignment ems and Nkx6-2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001101028.1
• Gene: Nkx6-2 / 309095
• RGDID: 1307280
• Length: 277
• Species: Rattus norvegicus
• Alignment Length: 256
• Identity: 81/256 - (31%)
• Similarity: 107/256 - (41%)
• Gaps: 59/256 - (23%)

  Fly   255 PMMMPGMPPAGLVRPFPMGPGGPPMPQGQP-GLPDIKALP------------PYINAPPELPPQH 306
            |..:.|  |||...| .:|..|..:|.|.| |:.||...|            |.:|
  Rat    31 PYALQG--PAGFKTP-ALGSLGAQLPLGTPHGISDILGRPVGAAGGGLLGSLPRLN--------- 83

  Fly   307 NPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPN------PGMARDSYQLYPWLL 365
                        ..|..||...||  |||.|.|.|...|: :|.      ||:.:.|    ||
  Rat    84 ------------GLASSAGVYFGP--AAAVARGYPKPLAE-LPGRPPIFWPGVVQGS----PW-- 127

  Fly   366 SRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSET 430
             |..|:......|..|....:| |..|..||..|:..||..||..:|:.|.||..||.:|.::|:
  Rat   128 -RDPRLAGSAQAGGVLDKDGKK-KHSRPTFSGQQIFALEKTFEQTKYLAGPERARLAYSLGMTES 190

  Fly   431 QVKVWFQNRRTK----HKRMQQEDEKGGEGGSQRNMHNGSGDEDDDELIDMEMDECPSDEE 487
            ||||||||||||    |.......:|..:..:::....||..||||| .:..:|....||:
  Rat   191 QVKVWFQNRRTKWRKRHAAEMASAKKKQDSDAEKLKVGGSDAEDDDE-YNRPLDPNSDDEK 250

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	30/59 (51%)
Nkx6-2	NP_001101028.1	Homeodomain	147..205	CDD:459649	30/58 (52%)