DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ems and dlx2b

DIOPT Version :9

Sequence 1:	NP_731868.1	Gene:	ems / 41697	FlyBaseID:	FBgn0000576	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_571372.1	Gene:	dlx2b / 30557	ZFINID:	ZDB-GENE-980526-18	Length:	276	Species:	Danio rerio

Alignment Length:	165	Identity:	54/165 - (32%)
Similarity:	75/165 - (45%)	Gaps:	33/165 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   323 QAGHVLGPAAAAAAAAGLPP------HAAQFMPNPGMARDSYQLYPWLLSRHGR------IFPHR 375
            |.||..|.|.|..|:....|      |.:....:.|.| .||..|    ..:|.      ..|.:
Zfish    49 QTGHCAGTAYAQLASYSYHPGTVGNVHYSPKAYDLGYA-SSYGAY----GTYGASSSPTPTEPEK 108

  Fly   376 FPGSFLVPPFR----KPKRI---RTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVK 433
            ....   |..|    |||::   ||.:|..||..|:..|:..||:...||..||.:|.|::||||
Zfish   109 EESE---PEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVK 170

  Fly   434 VWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGD 468
            :||||||:|.|::.    |.||..:.:.:  .|||
Zfish   171 IWFQNRRSKFKKLW----KNGEIPADQQV--ASGD 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	26/51 (51%)
dlx2b	NP_571372.1	DLL_N	29..102	CDD:289198	15/57 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	97..123		4/28 (14%)
		Homeobox	128..181	CDD:278475	26/52 (50%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	191..238		3/11 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810