Protein Alignment ems and ALX3

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_006483.2
• Gene: ALX3 / 257
• HGNCID: 449
• Length: 343
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 85/292 - (29%)
• Similarity: 109/292 - (37%)
• Gaps: 84/292 - (28%)

  Fly   198 IQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMP 262
            :.|.|..|..|.|       :|...::|         ..:||.....||      |.|.:.|. |
Human     1 MDPEHCAPFRVGP-------APGPYVAS---------GDEPPGPQGTPA------AAPHLHPA-P 42

  Fly   263 PAG--LVRPFP-MGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQA 324
            |.|  |.| || .||..|.:|  :|..|..|.|       .:|.|              ..||..
Human    43 PRGPRLTR-FPACGPLEPYLP--EPAKPPAKYL-------QDLGP--------------GPALNG 83

  Fly   325 GHVL-GPAAA------AAAAAGLP----------PHAAQFMPNPGMARDSYQLYPWLLSRHGRIF 372
            ||.. |||.|      ||:...||          |...|..|.|.:|.....|.|.|
Human    84 GHFYEGPAEAEEKTSKAASFPQLPLDCRGGPRDGPSNLQGSPGPCLASLHLPLSPGL-------- 140

  Fly   373 PHRFPGSF-LVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWF 436
                |.|. |.....|.:|.||.||..||.:||..|:...|.....|:.||...:|:|.:|:|||
Human   141 ----PDSMELAKNKSKKRRNRTTFSTFQLEELEKVFQKTHYPDVYAREQLALRTDLTEARVQVWF 201

  Fly   437 QNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGD 468
            ||||.|.::.    |:.|:....||....:.|
Human   202 QNRRAKWRKR----ERYGKIQEGRNPFTAAYD 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	25/55 (45%)
ALX3	NP_006483.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..104		41/149 (28%)
		PRK12323	<13..131	CDD:481241	43/164 (26%)
		Homeodomain	154..210	CDD:459649	25/55 (45%)