Protein Alignment ems and Gbx1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_056554.1
• Gene: Gbx1 / 231044
• MGIID: 95667
• Length: 418
• Species: Mus musculus
• Alignment Length: 442
• Identity: 105/442 - (23%)
• Similarity: 140/442 - (31%)
• Gaps: 197/442 - (44%)

  Fly   164 LSPETEQPQMAVSLKRERSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHA 228
            :|||.:.|                     ||..|..||:          .:.|::|     .||.
Mouse     1 MSPEGDTP---------------------NPPARPLPPY----------ERESAAP-----EPHC 29

  Fly   229 TPPQQQQQQPPPNYPKP-------------AMMH------PGGAG-------------------- 254
            ..|..::...|....:|             ||..      |||:|
Mouse    30 AEPAPRRHLGPRARSEPCVSARGARRGPGSAMQRAAGGGAPGGSGGSSGGPGAAFSIDSLIGPPP 94

  Fly   255 -----------PMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGL---------------------- 286
                       ||.||..|   ||.|..:.|.  |:|.|.|.|
Mouse    95 PRSGHLLYTGYPMFMPYRP---LVLPQALAPA--PLPAGLPPLAPLASFAGRLSNTFCAGLGQAV 154

  Fly   287 PDIKALP---PYINAPPEL---PPQHNPHLIAAAQFQMAA-------------ALQAGHVLGPA- 331
            |.:.||.   |....||:.   ||:     :|||....|:             ||.|..:| ||
Mouse   155 PSMVALTTALPSFAEPPDAYYGPPE-----LAAAAASTASRSNPEPAARRTDGALDAEELL-PAR 213

  Fly   332 -AAAAAAAGLPPHAAQFMPN-PGMAR----DSYQLYP----------------------WLLSRH 368
             .........|||.::..|: |...:    |..:|.|                      :|.|..
Mouse   214 EKVTEPPPPPPPHFSETFPSLPAEGKVYSSDEEKLEPPAGDPAGSEQEEEGSGGDSEDSFLDSSA 278

  Fly   369 GRIFPHRFPGSFLVP------------------------PFRKPKRIRTAFSPSQLLKLEHAFES 409
            |.      ||:.|.|                        |..|.:|.||||:..|||:||..|..
Mouse   279 GG------PGALLGPKPKLKGSPGTGAEEGTPVATGVTTPGGKSRRRRTAFTSEQLLELEKEFHC 337

  Fly   410 NQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRN 461
            .:|:...||..:|..|.|||.|||:||||||.|.||::..:.....|...||
Mouse   338 KKYLSLTERSQIAHALKLSEVQVKIWFQNRRAKWKRIKAGNVSSRSGEPVRN 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)
Gbx1	NP_056554.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..90		22/124 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..320		18/111 (16%)
		Homeodomain	317..373	CDD:459649	29/55 (53%)