Protein Alignment ems and Dbx2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_997416.2
• Gene: Dbx2 / 223843
• MGIID: 107445
• Length: 377
• Species: Mus musculus
• Alignment Length: 360
• Identity: 94/360 - (26%)
• Similarity: 134/360 - (37%)
• Gaps: 115/360 - (31%)

  Fly   131 PGTPKSHQDIQELLQRLHHNAAMASGL--SPLQTRLSPETEQPQMAVSLK-RERSPAPPAMEQAE 192
            |.||..     .:|:.|..:|..:..|  .||:.:.||.:..|..|:||. |.|||        .
Mouse     4 PDTPSI-----PVLKTLSGSADRSRTLPEEPLRAKDSPLSPDPVRALSLSLRTRSP--------R 55

  Fly   193 NPAQRIQPPHTPPKSVSPQSSQ----PSSSPTLLISSP----------------------HATPP 231
            .|.||.:.  ..|.:|:.|:..    .:||....:.:|                      ||.||
Mouse    56 LPGQRART--MLPSAVAAQAGAYWDVVASSALFGLPAPGFGSLGKSFLIENLLRAGAGPTHAPPP 118

  Fly   232 QQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGP-------PMPQGQ-PGLPD 288
                       |:||   ||...|.:.|  .||..| |..:.|.||       .||.|: ||..|
Mouse   119 -----------PRPA---PGPECPQLRP--LPASPV-PLKLCPAGPFGVRWAFQMPPGRAPGERD 166

  Fly   289 IKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAA---GLPPHAAQFMPN 350
            ..       ..|..|....|.|::|..|..|..  .|....||:..|.:.   |||.
Mouse   167 SA-------FQPSAPVPSKPFLLSAPPFYSACC--GGSCRRPASPTAFSREEHGLPL-------- 214

  Fly   351 PGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVG 415
              :.:||..     .:|.|.:                   .|..||..|...||..|:..:|:..
Mouse   215 --LTQDSNS-----KARRGIL-------------------RRAVFSEEQRKALEKMFQKQKYISK 253

  Fly   416 AERKALAQNLNLSETQVKVWFQNRRTKHKRMQQED 450
            .:|:.||.:|.|.|:|||:||||||.|.:..::::
Mouse   254 TDRRKLAVSLGLKESQVKIWFQNRRMKWRNSKEKE 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
Dbx2	NP_997416.2	COG5576	<217..334	CDD:227863	28/96 (29%)
		Homeodomain	229..283	CDD:459649	24/53 (45%)