Protein Alignment ems and EVX1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001980.1
• Gene: EVX1 / 2128
• HGNCID: 3506
• Length: 407
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 72/260 - (27%)
• Similarity: 97/260 - (37%)
• Gaps: 63/260 - (24%)

  Fly   200 PPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPP- 263
            |...||:.:.|:.          ..||.|.||..:::.......:|.   .|.||....||..|
Human    34 PLPEPPEKMVPRG----------CLSPRAVPPATRERGGGGPEEEPV---DGLAGSAAGPGAEPQ 85

  Fly   264 -AGLVRPFPMGPGGPPMP-------QGQPGLPDIKALPPYINAPPELPPQHNPHLIAA-AQFQMA 319
             ||...   :|| |||.|       ||||...|.::     :...|:.....|..... |::|
Human    86 VAGAAM---LGP-GPPAPSVDSLSGQGQPSSSDTES-----DFYEEIEVSCTPDCATGNAEYQ-- 139

  Fly   320 AALQAGHVLGPAAAAAAAAGLPPHAAQFMP--NPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLV 382
                  |..|..:.|...:   |:.....|  |.|......|                  |:...
Human   140 ------HSKGSGSEALVGS---PNGGSETPKSNGGSGGGGSQ------------------GTLAC 177

  Fly   383 PPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQ 447
            ....:.:|.||||:..|:.:||..|....||....|..||..|||.||.:||||||||.|.||.:
Human   178 SASDQMRRYRTAFTREQIARLEKEFYRENYVSRPRRCELAAALNLPETTIKVWFQNRRMKDKRQR 242

  Fly   448  447
            Human   243  242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	28/55 (51%)
EVX1	NP_001980.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	29..120		29/107 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..179		10/70 (14%)
		Homeodomain	184..240	CDD:459649	28/55 (51%)