Protein Alignment ems and Nkx1-2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_033149.1
• Gene: Nkx1-2 / 20231
• MGIID: 104806
• Length: 305
• Species: Mus musculus
• Alignment Length: 141
• Identity: 51/141 - (36%)
• Similarity: 67/141 - (47%)
• Gaps: 40/141 - (28%)

  Fly   329 GPAAAAAAAAGLPPHAAQFMP-NPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVP-PFR----- 386
            |...|.|.|.|.....|:.:| :||.                       |||   | |.|
Mouse   113 GSPEARAVAVGTEESGAEGLPASPGS-----------------------PGS---PRPRRRRAES 151

  Fly   387 ---KPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQ 448
               ||:|.||||:..||:.||:.|.:.:|:...||..||.:|:|:|||||:||||||||.|:
Mouse   152 SCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK--- 213

  Fly   449 EDEKGGEGGSQ 459
             ...|.:|..|
Mouse   214 -QNPGADGAVQ 223

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	30/55 (55%)
Nkx1-2	NP_033149.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..158		17/70 (24%)
		Homeodomain	157..213	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..257		5/18 (28%)