Protein Alignment ems and EMX1

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_004088.2
• Gene: EMX1 / 2016
• HGNCID: 3340
• Length: 290
• Species: Homo sapiens
• Alignment Length: 300
• Identity: 105/300 - (35%)
• Similarity: 129/300 - (43%)
• Gaps: 84/300 - (28%)

  Fly   197 RIQPPHTPPKSVSPQSSQPSSSPTLLISS------------------PH--ATPPQQQQQQPPP- 240
            |.:.|.|.|.:.:  ..||::.....|.|                  .|  |....::..:|..
Human    21 RARLPRTAPAAAT--MFQPAAKRGFTIESLVAKDGGTGGGTGGGGAGSHLLAAAASEEPLRPTAL 83

  Fly   241 NYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQ 305
            |||     ||..|....:.|.|.|..........|||.:           ..|..:|.|
Human    84 NYP-----HPSAAEAAFVSGFPAAAAAGAGRSLYGGPEL-----------VFPEAMNHP------ 126

  Fly   306 HNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHA---AQFMPNPGMARDSYQLYPWLLSR 367
                         |..:...|.||      |:...|||:   ||.       ||....|||:|
Human   127 -------------ALTVHPAHQLG------ASPLQPPHSFFGAQH-------RDPLHFYPWVL-- 163

  Fly   368 HGRIFPHRF-------PGSFLVPPF-RKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQN 424
            ..|.|.|||       .|..|..|| ||||||||||||||||:||.|||.|.||||||||.||.:
Human   164 RNRFFGHRFQASDVPQDGLLLHGPFARKPKRIRTAFSPSQLLRLERAFEKNHYVVGAERKQLAGS 228

  Fly   425 LNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHN 464
            |:||||||||||||||||:||.:.|:|.......::..|:
Human   229 LSLSETQVKVWFQNRRTKYKRQKLEEEGPESEQKKKGSHH 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	43/51 (84%)
EMX1	NP_004088.2	COG5576	140..>251	CDD:227863	71/119 (60%)
		Homeobox	196..248	CDD:278475	43/51 (84%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..257		31/40 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	158	1.000	Inparanoid score	I4276
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000921
OrthoInspector	1	1.000	-	-		mtm8552
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.820