DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ems and ceh-2

DIOPT Version :9

Sequence 1:	NP_731868.1	Gene:	ems / 41697	FlyBaseID:	FBgn0000576	Length:	494	Species:	Drosophila melanogaster
Sequence 2:	NP_491746.1	Gene:	ceh-2 / 191615	WormBaseID:	WBGene00000429	Length:	209	Species:	Caenorhabditis elegans

Alignment Length:	173	Identity:	77/173 - (44%)
Similarity:	92/173 - (53%)	Gaps:	31/173 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   308 PHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPW---LLSRHG 369
            ||:      |||.:       .|..:...|:|    :.....|.|.....:| :||   |.|...
Worm    62 PHV------QMACS-------NPFISGIGASG----SGDQNLNTGAGGSVWQ-HPWLELLQSTTA 108

  Fly   370 RIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKV 434
            ..|.....|.|| .|.||.||||||||.|||::||.|||.|.||||.|||.||..|:|:||||||
Worm   109 AQFGDVTAGLFL-QPLRKNKRIRTAFSASQLIQLEKAFEGNHYVVGNERKQLAAKLSLTETQVKV 172

  Fly   435 WFQNRRTKHKRMQQEDEKGGEGGSQRN--MHNGSGDEDDDELI 475
            |||||||||||::.|       ||..|  |.|...||||.:.:
Worm   173 WFQNRRTKHKRVRLE-------GSDPNAPMSNDEDDEDDKKSV 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	39/51 (76%)
ceh-2	NP_491746.1	Homeobox	130..182	CDD:278475	39/51 (76%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I4406
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000921
OrthoInspector	1	1.000	-	-		otm14654
orthoMCL	1	0.900	-	-		OOG6_132317
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	9	8.670