Protein Alignment ems and cog-1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001022264.1
• Gene: cog-1 / 175149
• WormBaseID: WBGene00000584
• Length: 256
• Species: Caenorhabditis elegans
• Alignment Length: 341
• Identity: 85/341 - (24%)
• Similarity: 123/341 - (36%)
• Gaps: 105/341 - (30%)

  Fly   124 LLMQQQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSLKRERSPAPPAM 188
            |:|.:....|....:|::   .|.|.:....|.|                 :..|:|.||:..:.
 Worm     3 LIMSEPPQLTTPDDKDVE---NRKHSSTYSISNL-----------------LLEKKESSPSGSSS 47

  Fly   189 EQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGA 253
            |  ::.|.........|.:.|.....|:||.:   ||..||.|.|...|         :|..|||
 Worm    48 E--DDSASSNDDDQRSPSATSSFIFPPASSSS---SSESATSPTQIMAQ---------LMANGGA 98

  Fly   254 GPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPH--LIAAAQF 316
                                        ..|||.....|         |..|.|..  :....|.
 Worm    99 ----------------------------VDPGLQAYFFL---------LQSQLNSQSMMNRVTQE 126

  Fly   317 QMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFL 381
            .::.||.:.::|.         .||.......| .|..:.|.||.|..|:
 Worm   127 NVSRALTSFNLLN---------NLPGALPSLSP-MGRLQHSMQLSPNSLN--------------- 166

  Fly   382 VPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRM 446
                .:.|:.|..|:..|:.:||..||..:|:.||:|..|||.||:||:||||||||||||.::.
 Worm   167 ----MQKKQSRPTFTGHQIYQLERKFEQTKYLAGADRAQLAQELNMSESQVKVWFQNRRTKWRKK 227

  Fly   447 QQEDE---KGGEGGSQ 459
            :..|.   |.|..|.:
 Worm   228 EAADNALVKRGASGDK 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	31/55 (56%)
cog-1	NP_001022264.1	Homeodomain	170..226	CDD:459649	31/55 (56%)