Protein Alignment ems and DLX6

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_005213.3
• Gene: DLX6 / 1750
• HGNCID: 2919
• Length: 293
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 77/284 - (27%)
• Similarity: 92/284 - (32%)
• Gaps: 125/284 - (44%)

  Fly   232 QQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYI 296
            |||||||||  |.|.                              ||.|..|...|
Human    39 QQQQQQPPP--PPPP------------------------------PPQPHSQQSSP--------- 62

  Fly   297 NAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQF----MPNPGMARDS 357
                                .||.|....|.|..|||||||.....|..|.    .|......:|
Human    63 --------------------AMAGAHYPLHCLHSAAAAAAAGSHHHHHHQHHHHGSPYASGGGNS 107

  Fly   358 Y--------------QLYPWLLSRH-----------------------GRIFPHRFPGSFLVPPF 385
            |              |..|:|.|.|                       |.|   ||.|.  ....
Human   108 YNHRSLAAYPYMSHSQHSPYLQSYHNSSAAAQTRGDDTDQQKTTVIENGEI---RFNGK--GKKI 167

  Fly   386 RKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQED 450
            |||   ||.:|..||..|.|.|:..||:...||..||.:|.|::||||:||||:|:|.|::
Human   168 RKP---RTIYSSLQLQALNHRFQQTQYLALPERAELAASLGLTQTQVKIWFQNKRSKFKKL---- 225

  Fly   451 EKGGEGGSQRNMHNGSGDEDDDEL 474
                       :..||...:.|.|
Human   226 -----------LKQGSNPHESDPL 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	26/55 (47%)
DLX6	NP_005213.3	Homeodomain	168..224	CDD:459649	29/58 (50%)