Protein Alignment ems and Hoxd4

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_034599.2
• Gene: Hoxd4 / 15436
• MGIID: 96208
• Length: 250
• Species: Mus musculus
• Alignment Length: 225
• Identity: 65/225 - (28%)
• Similarity: 85/225 - (37%)
• Gaps: 52/225 - (23%)

  Fly   237 QPPPNYPKPAMMHP--GGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAP 299
            ||...||:|.....  ||.||.....:|..|    ....|.||....|.||    :..|    ||
Mouse    47 QPSGLYPRPDFGEQPFGGGGPGPGSALPARG----HGQEPSGPGSHYGAPG----ERCP----AP 99

  Fly   300 PELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMA-RDSYQLYPW 363
            |..|              :..|.......||.                .|.||.| :....:|||
Mouse   100 PPAP--------------LPGARACSQPTGPK----------------QPPPGTALKQPAVVYPW 134

  Fly   364 LLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLS 428
            :...|.......:.|.       :|||.|||::..|:|:||..|..|:|:....|..:|..|.||
Mouse   135 MKKVHVNSVNPNYTGG-------EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHTLCLS 192

  Fly   429 ETQVKVWFQNRRTKHKRMQQEDEKGGEGGS 458
            |.|:|:||||||.|.|:..:.....|...|
Mouse   193 ERQIKIWFQNRRMKWKKDHKLPNTKGRSSS 222

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
Hoxd4	NP_034599.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	31..126		29/120 (24%)
		Antp-type hexapeptide	131..136		3/4 (75%)
		Homeodomain	153..209	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	210..250		2/13 (15%)