Protein Alignment ems and Hoxd3

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_034598.2
• Gene: Hoxd3 / 15434
• MGIID: 96207
• Length: 433
• Species: Mus musculus
• Alignment Length: 292
• Identity: 80/292 - (27%)
• Similarity: 115/292 - (39%)
• Gaps: 96/292 - (32%)

  Fly   201 PHTPPKSV-SPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGA--GPMMMPGMP 262
            |:.||.:. |..|..|||:.::..|:|...|                 .|.|..  |..|.||..
Mouse    49 PYPPPAAANSLDSDYPSSACSIQSSAPLRAP-----------------AHKGAELNGSCMRPGTG 96

  Fly   263 PAGLVRPFPMGPGGPPMPQG-----QPGLPDIKALPPYINAPPELPPQH--NPHLIAAAQFQMAA 320
            .:       .|.||...|.|     ||..|.    ||   .||.|||..  ||          .:
Mouse    97 NS-------QGGGGGNQPPGLNSEQQPPQPP----PP---PPPTLPPSSPTNP----------GS 137

  Fly   321 ALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLL-SRHGRIFPHRFPGSFLV-- 382
            .:.|....|..:|:::::.:                |.|::||:. ||..    .:...|...
Mouse   138 GVPAKKTKGGLSASSSSSTI----------------SKQIFPWMKESRQN----SKQKNSCATSG 182

  Fly   383 -------PPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRR 440
                   ||....||:|||::.:||::||..|..|:|:....|..:|..|||:|.|:|:||||||
Mouse   183 ENCEDKSPPGPASKRVRTAYTSAQLVELEKEFHFNRYLCRPRRVEMANLLNLTERQIKIWFQNRR 247

  Fly   441 TKHKRMQ-----------QEDEK----GGEGG 457
            .|:|:.|           |..|:    ||..|
Mouse   248 MKYKKDQKAKGILHSPAGQSPERSPPLGGAAG 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	27/55 (49%)
Hoxd3	NP_034598.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	44..198		47/209 (22%)
		Antp-type hexapeptide	161..166		2/4 (50%)
		Homeodomain	196..252	CDD:459649	27/55 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	258..280		5/22 (23%)
		DUF4074	370..431	CDD:463833
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	401..433