Protein Alignment ems and Hoxd11

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_032299.1
• Gene: Hoxd11 / 15431
• MGIID: 96203
• Length: 336
• Species: Mus musculus
• Alignment Length: 428
• Identity: 86/428 - (20%)
• Similarity: 130/428 - (30%)
• Gaps: 157/428 - (36%)

  Fly    68 PPATLTLIPG-----------SPPHHLMAPPAHGLPYPHPHAQQQHLQAPHPHPHLSPAQQHVLH 121
            |.|....:||           |.|..|..|.:..:.:|:         :.:..||:.|.::....
Mouse     9 PSAASMYLPGCAYYVAPSDFASKPSFLSQPSSCQMTFPY---------SSNLAPHVQPVREVAFR 64

  Fly   122 QHLLMQQQHP--------------GTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQ 172
            .:.|.:.:.|              |.|..             ....:.|.:|.....:.......
Mouse    65 DYGLERAKWPYRGGGGGGAGGGGGGGPGG-------------GGGGSGGYAPYYAAAAAAAAAAA 116

  Fly   173 MAVSLKRERSPAPPA------MEQAENPAQRIQ-PPHTPPKSVS------------PQSSQP--S 216
            .|.....:|...|||      :.:|..|..... |||.|..:.|            ||....  .
Mouse   117 AAEEAAMQRDLLPPAGRRPDVLFKAPEPVCGAPGPPHGPAAAASNFYSAVGRNGILPQGFDQFYE 181

  Fly   217 SSPTLLISSPHATPPQQQQQQPPPNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQ 281
            ::|    ..|.|.|    |.||.|..|:|             .|....|..:|...|.||.|..:
Mouse   182 AAP----GPPFAGP----QPQPAPAPPQP-------------EGAADKGDPKPGAGGGGGSPCAK 225

  Fly   282 GQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQ 346
            ..|| |:.|.                           ||....|...||...|.|.
Mouse   226 ATPG-PEPKG---------------------------AAEGGGGEGEGPPGEAGAE--------- 253

  Fly   347 FMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQ 411
                               ...|.:.|.|            .::.|..::..|:.:||..|..|.
Mouse   254 -------------------KSGGTVAPQR------------SRKKRCPYTKYQIRELEREFFFNV 287

  Fly   412 YVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQE 449
            |:...:|..|::.|||::.|||:||||||.|.|::.::
Mouse   288 YINKEKRLQLSRMLNLTDRQVKIWFQNRRMKEKKLNRD 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	22/55 (40%)
Hoxd11	NP_032299.1	DUF3528	26..187	CDD:432284	29/186 (16%)
		Homeodomain	265..321	CDD:459649	22/55 (40%)