Protein Alignment ems and Hoxa4

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_032291.1
• Gene: Hoxa4 / 15401
• MGIID: 96176
• Length: 285
• Species: Mus musculus
• Alignment Length: 281
• Identity: 82/281 - (29%)
• Similarity: 104/281 - (37%)
• Gaps: 81/281 - (28%)

  Fly   185 PPAMEQAENPAQRIQPPHTPP------KSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPP---- 239
            ||..|.|         ||..|      ....|...:|.|:|.|...:|||.      :|||
Mouse    18 PPFEEFA---------PHGGPGGGDGAVGGGPGYPRPQSAPHLPAPNPHAA------RQPPAYYA 67

  Fly   240 -----PNYPKPAMMHPGGAGPMMMPGMPPAGLVRPFPM-GPGGPPMPQGQPGLPDIKALPPYINA 298
                 |:||......|..|.|....|..||   ||... .||..|.|..|
Mouse    68 PRAREPSYPGGLYPAPAAACPYACRGASPA---RPEQSPAPGAHPSPAPQ--------------- 114

  Fly   299 PPELPPQH-NPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQ--- 359
             |..||:| .|                    ||...|.|..|..|.....:.:.|.|....:
Mouse   115 -PPAPPRHCAP--------------------GPTTPAVATGGSAPACPLLLADQGPAGPKGKEPV 158

  Fly   360 LYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQN 424
            :|||:...|.......:.|.       :|||.|||::..|:|:||..|..|:|:....|..:|..
Mouse   159 VYPWMKKIHVSAVNSSYNGG-------EPKRSRTAYTRQQVLELEKEFHFNRYLTRRRRIEIAHT 216

  Fly   425 LNLSETQVKVWFQNRRTKHKR 445
            |.|||.|||:||||||.|.|:
Mouse   217 LCLSERQVKIWFQNRRMKWKK 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	28/55 (51%)
Hoxa4	NP_032291.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	19..70		17/65 (26%)
		PHA03247	<43..161	CDD:223021	39/162 (24%)
		Antp-type hexapeptide	159..164		3/4 (75%)
		Homeodomain	181..237	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..285		82/281 (29%)