Protein Alignment ems and Hoxa2

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_034581.1
• Gene: Hoxa2 / 15399
• MGIID: 96174
• Length: 372
• Species: Mus musculus
• Alignment Length: 273
• Identity: 80/273 - (29%)
• Similarity: 108/273 - (39%)
• Gaps: 77/273 - (28%)

  Fly   204 PPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQP---PPNYPKPAMMHPGGAGPMMMPGMPPAG 265
            ||.:   .:.|.||..|..:|.....||..:|..|   |.::|:    |..|.|     |.|.:.
Mouse    26 PPVA---DTFQSSSIKTSTLSHSTLIPPPFEQTIPSLNPGSHPR----HGAGVG-----GRPKSS 78

  Fly   266 LVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGP 330
                 |.|..|.|:|.|        ||     .|||.|....
Mouse    79 -----PAGSRGSPVPAG--------AL-----QPPEYPWMKE----------------------- 102

  Fly   331 AAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAF 395
             ..||....|||.||...|.....::|.:           |......||         :|:|||:
Mouse   103 -KKAAKKTALPPAAASTGPACLGHKESLE-----------IADGSGGGS---------RRLRTAY 146

  Fly   396 SPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQR 460
            :.:|||:||..|..|:|:....|..:|..|:|:|.||||||||||.||||..|..|.....|..:
Mouse   147 TNTQLLELEKEFHFNKYLCRPRRVEIAALLDLTERQVKVWFQNRRMKHKRQTQCKENQNSEGKFK 211

  Fly   461 NMHNGSGDEDDDE 473
            |:.:....|:|:|
Mouse   212 NLEDSDKVEEDEE 224

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/55 (53%)
Hoxa2	NP_034581.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	48..95		19/73 (26%)
		Antp-type hexapeptide	96..101		2/4 (50%)
		Homeodomain	140..196	CDD:459649	29/55 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	194..225		10/31 (32%)