Protein Alignment ems and Hmx1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_034575.1
• Gene: Hmx1 / 15371
• MGIID: 107178
• Length: 332
• Species: Mus musculus
• Alignment Length: 313
• Identity: 77/313 - (24%)
• Similarity: 109/313 - (34%)
• Gaps: 104/313 - (33%)

  Fly   204 PPKSVSPQSSQPSSSPTLLISS----------------------------PHATPPQQQQQQPPP 240
            |.:...|..:.|:.:.:.||.:                            |....|:|.:::...
Mouse     2 PDELTEPGRATPARASSFLIENLLAAEAKGAGRSTQGDGVREEEEEDDDDPEDEDPEQARRRLQR 66

  Fly   241 NYPKPAMMHPGGAGPMMMPGM---PPAGLVRPFPMGPGG-----PPMPQGQPG--LPD------- 288
            ...:.|...|||.......|:   ||.|...||.:|.||     |.:..|..|  .||
Mouse    67 RRQQRAGSGPGGEARARALGLGPRPPPGPGPPFALGCGGTTRWYPRVHGGYGGGLSPDTSDRDSP 131

  Fly   289 --------IKALPPYINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAA 345
                    .::..|....|..:|.:......|....:.|...:|     ||.||||.
Mouse   132 ETGEEMGRAESAWPRCPGPGTVPREVTTQGPATGGEEAAELAEA-----PAVAAAAT-------- 183

  Fly   346 QFMPNPGMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESN 410
                  |.||..                             :.|:.||.||.||:.:||..|:..
Mouse   184 ------GEARGG-----------------------------RRKKTRTVFSRSQVFQLESTFDLK 213

  Fly   411 QYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRM---QQEDEKGGEGGSQR 460
            :|:..|||..||.:|.|:|||||:||||||.|.||.   :.|.......|:||
Mouse   214 RYLSSAERAGLAASLQLTETQVKIWFQNRRNKWKRQLAAELEAASLSPPGAQR 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	30/55 (55%)
Hmx1	NP_034575.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	28..170		25/141 (18%)
		Homeodomain	192..248	CDD:459649	30/55 (55%)
		HMX family specific domain 1	251..261		1/9 (11%)
		HMX family specific domain 2	264..277		2/3 (67%)