Protein Alignment ems and Mnx1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_064328.2
• Gene: Mnx1 / 15285
• MGIID: 109160
• Length: 404
• Species: Mus musculus
• Alignment Length: 372
• Identity: 105/372 - (28%)
• Similarity: 139/372 - (37%)
• Gaps: 150/372 - (40%)

  Fly   206 KSVSPQSSQPSSSP--TLLISSPHATPPQQQQQQPPPN--------YPKPAMMHPGGAGPMMMPG 260
            :|.||.||:.:::|  .|...||           .||.        .|||..:..||.|
Mouse    57 RSCSPASSEATAAPGDRLRAESP-----------SPPRLLAAHCALLPKPGFLGAGGGG------ 104

  Fly   261 MPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPH--LIAAAQFQMAAALQ 323
             ..||       |||                           .|.|:.|  ..|||....|||..
Mouse   105 -GAAG-------GPG---------------------------TPHHHAHPGAAAAAAAAAAAAAA 134

  Fly   324 AGHVLG---------------------------PAAAAAAAAGLPPHAAQFMP-----NPGMARD 356
            .|..||                           .||||||.||..|..:...|     :|....|
Mouse   135 GGLALGLHPGGAQGGAGLPAQAALYGHPVYSYSAAAAAAALAGQHPALSYSYPQVQGAHPAHPAD 199

  Fly   357 -------SYQLYPWL-LSRHGRIFPHRFPGSFLVPPFR---------KPKRIRTAFSPSQLLKLE 404
                   ::||..|| .|..|.|.|.       :|.|.         |.:|.||||:..|||:||
Mouse   200 PIKLGASTFQLDQWLRASTAGMILPK-------MPDFSSQAQSNLLGKCRRPRTAFTSQQLLELE 257

  Fly   405 HAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKR---------MQQEDEKGGEGGSQR 460
            |.|:.|:|:...:|..:|.:|.|:|||||:||||||.|.||         .:.|.:|||.||:.:
Mouse   258 HQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWKRSKKAKEQAAQEAEKQKGGGGGTGK 322

  Fly   461 NMHNGSGDEDDDELI------------------DMEMDECPSDEEHE 489
               .||.::.::||:                  |.:.||...|||.:
Mouse   323 ---GGSEEKTEEELMGPPVSGDKASGRRLRDLRDSDPDEDEDDEEED 366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	30/55 (55%)
Mnx1	NP_064328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..80		9/33 (27%)
		Homeodomain	242..298	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..404		16/71 (23%)