DRSC/TRiP Functional Genomics Resources

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Protein Alignment ems and HHEX

DIOPT Version :10

Sequence 1:NP_731868.1 Gene:ems / 41697 FlyBaseID:FBgn0000576 Length:494 Species:Drosophila melanogaster
Sequence 2:XP_321747.6 Gene:HHEX / 1281788 VectorBaseID:AGAMI1_011400 Length:331 Species:Anopheles gambiae


Alignment Length:422 Identity:104/422 - (24%)
Similarity:150/422 - (35%) Gaps:159/422 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   116 QQHVLHQHLLMQQQHPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSLKRE 180
            ||.|..|:||.|                    ||:|:..:|.|              .|.||..|
Mosquito    20 QQRVEQQNLLYQ--------------------HHHASRLAGTS--------------TANSLSSE 50

  Fly   181 RSPAPPAMEQAENPAQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQQQQQPPPNYPKP 245
                                    |.|::  .|.|||..:.|.|  |..|..             
Mosquito    51 ------------------------PGSLT--HSAPSSYSSTLQS--HGIPTD------------- 74

  Fly   246 AMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQHNPHL 310
                ..|..|   ||.|.  |..|..:|.|.    .|..|...::      :..|:.|....|.|
Mosquito    75 ----CAGGTP---PGSPV--LASPLAIGSGS----TGGGGGGSVR------SESPKKPTAMYPGL 120

  Fly   311 IAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWLLSRHGRIFPHR 375
            :..::..:...||.|.   ||.....||.|..:|:.      :.:.|.:::|:        :|| 
Mosquito   121 LDFSKNVIPIPLQFGM---PAFNPLNAAYLEHYASV------LHKASPRVWPF--------YPH- 167

  Fly   376 FPGSFLVPPF---RKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQ 437
             |.|:|:|..   ||..::|  |:|.|...||..|.:::|:...:|:.||..|.||:.|||.|||
Mosquito   168 -PYSYLLPTCGSKRKGGQVR--FTPQQTQSLEKRFSNHKYLSPEDRRNLAIQLKLSDRQVKTWFQ 229

  Fly   438 NRRTKHKR-----MQQEDEKG-------------GEGGSQRNMHNGSGDEDDDE----------- 473
            |||.|.:|     .|..|..|             |.|.|:...:.|..|::||:           
Mosquito   230 NRRAKWRRANSGCQQSTDVLGSADGLGDASKASSGTGMSRTQKYLGEKDDEDDDDEGTARYGRRT 294

  Fly   474 --LIDME--MDECPS--------DEEHELDAS 493
              .||.:  ..:|.|        |||.:..||
Mosquito   295 PSSIDYDGKSSDCYSDRGSSEDRDEEEDDPAS 326

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
emsNP_731868.1 Homeodomain 389..445 CDD:459649 24/55 (44%)
HHEXXP_321747.6 None

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