Protein Alignment ems and Dr

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: XP_313452.5
• Gene: Dr / 1274345
• VectorBaseID: AGAMI1_005699
• Length: 386
• Species: Anopheles gambiae
• Alignment Length: 510
• Identity: 135/510 - (26%)
• Similarity: 177/510 - (34%)
• Gaps: 199/510 - (39%)

  Fly     5 IPPVPTAAAAVMMPTPKQK----IGFSIESIVGNDVSTAGGNSTPDLSGPQSPPPGERNV-PGSP 64
            :.||..|..:..:|..::.    ..||:.|::.:             :.|::|......: .|:|
Mosquito     9 VTPVRMAMTSPTVPMQQKSNSRISNFSVASLLAD-------------TRPKTPNAHHAIITSGTP 60

  Fly    65 PQTPPATLTLIPGSPPHHLMAPPAHGLPYPHPHAQQQHLQAPHPHPHLSPAQQHVLHQHLLMQQQ 129
            ..|.|...:|.|.||   ||   .|| | ||..|                    :|||
Mosquito    61 TTTTPTPPSLTPLSP---LM---VHG-P-PHGAA--------------------LLHQ------- 90

  Fly   130 HPGTPKSHQDIQELLQRLHHNAAMASGLSPLQTRLSPETEQPQMAVSLKRERSPAPPAMEQAENP 194
                                  ||.:.|:.:.|...|.|             ||:...:     |
Mosquito    91 ----------------------AMTTALTTVTTTTLPGT-------------SPSSDML-----P 115

  Fly   195 AQRIQPPHTPPKSVSPQSSQPSSSPTLLISSPHATPPQQ--QQQQPPPNYPK------------- 244
            |.  ...||...| ||:|....||...|.:..|...|..  :......|:.:
Mosquito   116 AN--LSSHTTSSS-SPRSQHDGSSLRNLDADRHTDTPHSLLESDDYDSNHDEEEDSIVDIEDMDQ 177

  Fly   245 ---PAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQPGLPDIKALPPYINAPPELPPQH 306
               .:...|||......||.|.|     ..||.|.||
Mosquito   178 ELSESGSQPGGRKGSGSPGSPSA-----MGMGHGSPP---------------------------- 209

  Fly   307 NPHLIAAAQFQMAAALQAGHV-LGP----AAAAAAAA------GLP-PHAAQFMP--NPGMARDS 357
                 .||   :|||  |||| :.|    |.||||||      |:| |.|.|..|  .||
Mosquito   210 -----GAA---LAAA--AGHVPIRPTPFSALAAAAAAWGGMSGGVPWPGARQMPPFGPPG----- 259

  Fly   358 YQLYPWLLSRHGRIFPHRFPGSFLVPP-----FRKPK---RIRTAFSPSQLLKLEHAFESNQYVV 414
              |:|      |:.|.....|....||     .||.|   :.||.|:..|||.||..|...||:.
Mosquito   260 --LFP------GQGFGAGQLGGDNEPPRIKCNLRKHKPNRKPRTPFTTQQLLSLEKKFREKQYLS 316

  Fly   415 GAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQ-EDEK------GGEGGSQRNM 462
            .|||...:.:|.|:|||||:||||||.|.||:|: |.||      |...|:|..|
Mosquito   317 IAERAEFSSSLRLTETQVKIWFQNRRAKAKRLQEAELEKIKMAALGRAPGAQLYM 371

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	29/58 (50%)
Dr	XP_313452.5	None