Protein Alignment ems and Alx4

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_031468.1
• Gene: Alx4 / 11695
• MGIID: 108359
• Length: 399
• Species: Mus musculus
• Alignment Length: 230
• Identity: 61/230 - (26%)
• Similarity: 83/230 - (36%)
• Gaps: 68/230 - (29%)

  Fly   235 QQQPPPNYPKPAMMHPGGAGPMMMPGMPPA------GLVRPFPMGPGGPPMPQGQPGLPDIKALP 293
            |.|||...|.||            |..|||      |..:..|  .|...:.:|..|......:|
Mouse    91 QPQPPTPQPPPA------------PPAPPAHLYLQRGACKTPP--DGSLKLQEGSGGHNAALQVP 141

  Fly   294 PYIN----APPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNPGMA 354
            .|..    ..|||||...|           ..:...::   :.....|.|....|:..:|:|...
Mouse   142 CYAKESNLGEPELPPDSEP-----------VGMDNSYL---SVKETGAKGPQDRASAEIPSPLEK 192

  Fly   355 RDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGAERK 419
            .||.       |..|                 |.:|.||.|:..||.:||..|:...|.....|:
Mouse   193 TDSE-------SNKG-----------------KKRRNRTTFTSYQLEELEKVFQKTHYPDVYARE 233

  Fly   420 ALAQNLNLSETQVKVWFQNRRTKHKR------MQQ 448
            .||...:|:|.:|:|||||||.|.::      |||
Mouse   234 QLAMRTDLTEARVQVWFQNRRAKWRKRERFGQMQQ 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
Alx4	NP_031468.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	68..133		15/55 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	171..206		11/58 (19%)
		Homeodomain	203..259	CDD:459649	24/55 (44%)
		OAR	375..393	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	379..392