Protein Alignment ems and Hoxc11

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_001020013.1
• Gene: Hoxc11 / 109663
• MGIID: 96193
• Length: 304
• Species: Mus musculus
• Alignment Length: 293
• Identity: 71/293 - (24%)
• Similarity: 109/293 - (37%)
• Gaps: 65/293 - (22%)

  Fly   180 ERSPAPPAMEQAENPAQRIQPPHT---PPKSVSPQSSQPSSS--PTLLISSPHATPPQQQQQQ-- 237
            |.|.....:.||  |:::|..|::   ||........:||..  .....||.:|...:...::
Mouse    43 EFSTVSSFLPQA--PSRQISYPYSAQVPPVREVSYGLEPSGKWHHRNSYSSCYAAADELMHRECL 105

  Fly   238 PPPNYPKPAMMHPGGAGPMMMPGMP---PAGLVRPFPMGPGGPPMPQ--------GQPGLPDIKA 291
            ||....:..|.:.|..|....|..|   |||.   :........:||        ...|..|..|
Mouse   106 PPSTVTEILMKNEGSYGGHHHPSAPHAAPAGF---YSSVNKNSVLPQAFDRFFDNAYCGGGDAPA 167

  Fly   292 LPP-----YINAPPELPPQHNPHLIAAAQFQMAAALQAGHVLGPAAAAAAAAGLPPHAAQFMPNP 351
            .||     .....||.||              |:.|          |:.|.||....|.:...||
Mouse   168 EPPCSGKGEAKGEPEAPP--------------ASGL----------ASRAEAGAEAEAEEENTNP 208

  Fly   352 GMARDSYQLYPWLLSRHGRIFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAFESNQYVVGA 416
            ..:..|:.             ..:.|.....|...:.::.|..:|..|:.:||..|..|.|:...
Mouse   209 SSSGSSHS-------------ATKEPAKGAAPNAPRTRKKRCPYSKFQIRELEREFFFNVYINKE 260

  Fly   417 ERKALAQNLNLSETQVKVWFQNRRTKHKRMQQE 449
            :|..|::.|||::.|||:||||||.|.|::.::
Mouse   261 KRLQLSRMLNLTDRQVKIWFQNRRMKEKKLSRD 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	23/55 (42%)
Hoxc11	NP_001020013.1	DUF3528	42..161	CDD:432284	26/122 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	167..237		19/106 (18%)
		Homeodomain	233..289	CDD:459649	23/55 (42%)