Protein Alignment ems and LBX1

DIOPT Version :10

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_006553.2
• Gene: LBX1 / 10660
• HGNCID: 16960
• Length: 281
• Species: Homo sapiens
• Alignment Length: 203
• Identity: 60/203 - (29%)
• Similarity: 88/203 - (43%)
• Gaps: 25/203 - (12%)

  Fly   292 LPPYINAPPELPPQHNPHLIAAAQFQMAAAL-QAGHVLGPAAAAAAAAGLP--PHAAQFMPNPGM 353
            |||..|:...|.|.....::.....:.:.:| .|.|:|. ||...|..|||  ..|.....:|..
Human    23 LPPPANSNKPLTPFSIEDILNKPSVRRSYSLCGAAHLLA-AADKHAQGGLPLAGRALLSQTSPLC 86

  Fly   354 ARDSYQLYPW-------LLSRHGR----IFPHRFPGSFLVPPFRKPKRIRTAFSPSQLLKLEHAF 407
            |.:......:       |.:..||    ||     |....|  :|.::.||||:..|:.:||..|
Human    87 ALEELASKTFKGLEVSVLQAAEGRDGMTIF-----GQRQTP--KKRRKSRTAFTNHQIYELEKRF 144

  Fly   408 ESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEKGGEGGSQRNMHNGSGDEDDD 472
            ...:|:..|:|..:||.|.|:..||..||||||.|.||..:|.:...|...:.   ..||..|..
Human   145 LYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKL---GPSGQMDIV 206

  Fly   473 ELIDMEMD 480
            .|.::|.:
Human   207 ALAELEQN 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeodomain	389..445	CDD:459649	24/55 (44%)
LBX1	NP_006553.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		5/11 (45%)
		Homeodomain	126..182	CDD:459649	24/55 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..281		0/1 (0%)