Protein Alignment ems and CDX4

DIOPT Version :9

• Sequence 1: NP_731868.1
• Gene: ems / 41697
• FlyBaseID: FBgn0000576
• Length: 494
• Species: Drosophila melanogaster
• Sequence 2: NP_005184.1
• Gene: CDX4 / 1046
• HGNCID: 1808
• Length: 284
• Species: Homo sapiens
• Alignment Length: 287
• Identity: 70/287 - (24%)
• Similarity: 102/287 - (35%)
• Gaps: 88/287 - (30%)

  Fly   244 KPAMMHPGGAGPMMMPGMPPAGLVRPFPMGPGGPPMPQGQ----------PGLPDIKALPPY--- 295
            |.|.|:|   |.:|.||  ..|.......|.||.|||...          .|.|.:.::.|:
Human     9 KEAGMYP---GTLMSPG--GDGTAGTGGTGGGGSPMPASNFAAAPAFSHYMGYPHMPSMDPHWPS 68

  Fly   296 --INAPPELPPQH----------------------NPHLIAAAQFQMAAAL-----------QAG 325
              :...|..||:.                      :|....:..:.....:           |||
Human    69 LGVWGSPYSPPREDWSVYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNLGPVGGGTSGSSLPGQAG 133

  Fly   326 HVLGPAAAAAAAAGLPPHAAQFMPNPGMARDSYQLYPWL---LSRHGRIFPHRFPGSFLVPPFRK 387
            ..|.|..|.||.|..|            :|..:..|.|:   :...|:.              |.
Human   134 GSLVPTDAGAAKASSP------------SRSRHSPYAWMRKTVQVTGKT--------------RT 172

  Fly   388 PKRIRTAFSPSQLLKLEHAFESNQYVVGAERKALAQNLNLSETQVKVWFQNRRTKHKRMQQEDEK 452
            .::.|..::..|.|:||..|..|:|:....:..||.||.|||.|||:||||||.|.::|.::..
Human   173 KEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKMIKKKI- 236

  Fly   453 GGEGGSQRNMHNGSGDEDDDELIDMEM 479
                 ||.....||...|.|.:...|:
Human   237 -----SQFENSGGSVQSDSDSISPGEL 258

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ems	NP_731868.1	Homeobox	392..444	CDD:278475	25/51 (49%)
CDX4	NP_005184.1	Caudal_act	13..162	CDD:309740	33/165 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		10/29 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..155		11/46 (24%)
		Homeobox	177..229	CDD:306543	25/51 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..259		6/21 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X14
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.810